Abstract
To determine the seroprevalence of astrovirus MLB1 (MLB1), an indirect enzyme-linked immunosorbent assay (ELISA) was established. MLB1 seropositivity was high in children <6 months old, decreased to a nadir at 12 to 23 months old, and increased to 100% by adulthood. MLB1 infection is common, and primary exposure occurs in childhood.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibodies, Viral / blood*
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Astroviridae Infections / epidemiology*
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Astroviridae Infections / immunology*
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Capsid / immunology
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Enzyme-Linked Immunosorbent Assay
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Feces / virology
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Humans
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Infant
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Mamastrovirus / classification
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Mamastrovirus / immunology*
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Open Reading Frames / immunology
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Seroepidemiologic Studies