Seroepidemiology of astrovirus MLB1

Clin Vaccine Immunol. 2014 Jun;21(6):908-11. doi: 10.1128/CVI.00100-14. Epub 2014 Apr 30.

Abstract

To determine the seroprevalence of astrovirus MLB1 (MLB1), an indirect enzyme-linked immunosorbent assay (ELISA) was established. MLB1 seropositivity was high in children <6 months old, decreased to a nadir at 12 to 23 months old, and increased to 100% by adulthood. MLB1 infection is common, and primary exposure occurs in childhood.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Viral / blood*
  • Astroviridae Infections / epidemiology*
  • Astroviridae Infections / immunology*
  • Capsid / immunology
  • Enzyme-Linked Immunosorbent Assay
  • Feces / virology
  • Humans
  • Infant
  • Mamastrovirus / classification
  • Mamastrovirus / immunology*
  • Open Reading Frames / immunology
  • Seroepidemiologic Studies

Substances

  • Antibodies, Viral