Mild Rh(III)-catalyzed direct C-H bond arylation of (hetero)arenes with arylsilanes in aqueous media

Org Lett. 2014 May 16;16(10):2614-7. doi: 10.1021/ol500754h. Epub 2014 Apr 30.

Abstract

An efficient rhodium(III)-catalyzed C-H bond activation and further direct arylation of (hetero)arenes with organosilanes in aqueous media was developed. This reaction shows good substrate scope and excellent functional group compatibility and gives the products in good yields with excellent regioselectivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Combinatorial Chemistry Techniques
  • Heterocyclic Compounds / chemical synthesis*
  • Heterocyclic Compounds / chemistry
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Rhodium / chemistry*
  • Silanes / chemistry*
  • Water

Substances

  • Heterocyclic Compounds
  • Silanes
  • Water
  • Rhodium