Tripodal molecules for the promotion of phosphoester hydrolysis

Chem Commun (Camb). 2014 Jun 14;50(47):6217-20. doi: 10.1039/c4cc00333k. Epub 2014 Apr 30.

Abstract

A series of low molecular weight tripodal amide/histidine-containing compounds (1-2) have been synthesised and shown to increase the rate of bis-(p-nitrophenyl) phosphate (BNPP) and soman (GD) breakdown in buffered aqueous solution.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemistry*
  • Esters / chemistry*
  • Histidine / chemistry*
  • Hydrolysis
  • Molecular Structure
  • Organophosphorus Compounds / chemistry*

Substances

  • Amides
  • Esters
  • Organophosphorus Compounds
  • Histidine