Ghana-Tokyo Medical and Dental University Research Collaboration Center has been established since 2008 when our Program was chosen together with the Program in the Philippines proposed by Tohoku University as an additional small-scale research center of the Overseas Research Program on Emerging and Reemerging Diseases that is funded by the Ministry of Education, Culture, Sports, Science and Technology of the Japanese Government and started in 2005. This 5-year government-supported Program has changed its name to develop into a more active world-level program called Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) and entered the second 5-year phase in 2010, and our Program is playing an important role among other research centers located in Asia and Africa. Currently, two research projects are carried out in parallel in Noguchi Memorial Institute for Medical Research by Tokyo Medical and Dental University: one is a J-GRID project and the other is the one of Science and Technology Research Partnership for Sustainable Development (SATREPS) which is a joint project between Japan International Cooperation Agency (JICA) and Japan Science and Technology Agency (JST). This special article is describing what these two projects are all about.