In between - Proteomics of dog biological fluids

J Proteomics. 2014 Jun 25:106:30-45. doi: 10.1016/j.jprot.2014.04.016. Epub 2014 Apr 22.

Abstract

Dogs are relevant to biomedical research in connection both to veterinary medicine for their role as pets and to basic investigations for their use as animal models in pathology, pharmacology and toxicology studies. Proteomic analysis of biological fluids is less advanced for dogs than for other animal species but a wealth of information has already been gathered, which we summarize in this review. As a remarkable feature, we also assemble here for due reference a number of 2-DE serum/plasma or urine patterns in health and disease; some of them correspond to unpublished data from the University of Veterinary Medicine Vienna.

Keywords: Animal model; Biological fluids; Dog/canine; Proteomics; Veterinary medicine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Allergens / chemistry
  • Animals
  • Blood Proteins / chemistry*
  • Body Fluids
  • Dogs
  • Electrophoresis, Gel, Two-Dimensional / methods*
  • Hydrogen-Ion Concentration
  • Models, Animal
  • Polysaccharides / chemistry
  • Proteinuria / metabolism
  • Proteomics / methods*
  • Silver Staining
  • Temperature
  • Urine / chemistry

Substances

  • Allergens
  • Blood Proteins
  • Polysaccharides