Substance P-like immunoreactivity in sympathetic ganglion from toad

Cell Mol Biol. 1989;35(3):325-31.

Abstract

Substance P-like immunoreactivity cellular in toad sympathetic ganglia was studied in normal and capsaicin-treated ganglia. In the eighth sympathetic ganglion substance P-like immunoreactive are found in mast cells and SIF cells. The effect of substance P (0.001-0.003 mM) caused increase of compound action potential during tetanical stimulation (50 Hz by 40 sec.) and post-tetanic potentiation (0.1 Hz). Our results show that substance P facilitates synaptic transmission in the sympathetic ganglia from Caudiverbera caudiverbera.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / drug effects
  • Animals
  • Anura
  • Capsaicin / pharmacology
  • Ganglia, Sympathetic / analysis*
  • Ganglia, Sympathetic / drug effects
  • Immunohistochemistry
  • Mast Cells / analysis*
  • Substance P / analysis*
  • Substance P / immunology
  • Substance P / pharmacology
  • Synaptic Transmission

Substances

  • Substance P
  • Capsaicin