[The new possibilities in serologic diagnostic of Ixodes mite-borne borreliosis using ImmunoChip]

T A Chekanova; M L Markelov; L C Karan'; M A Ushakova; E A Pudova; A C Romashkina; N P Kirdiashkina; I N Manzeniuk; A I Sazhin; E C Snarkaia; L P Anan'eva; G A Shipulin

[The new possibilities in serologic diagnostic of Ixodes mite-borne borreliosis using ImmunoChip]

Klin Lab Diagn. 2013 Dec:(12):51-5.

[Article in Russian]

Authors

T A Chekanova, M L Markelov, L C Karan', M A Ushakova, E A Pudova, A C Romashkina, N P Kirdiashkina, I N Manzeniuk, A I Sazhin, E C Snarkaia, L P Anan'eva, G A Shipulin

PMID: 24757867

Abstract

The new kit of reagents in format of the immunochip "ImmunoChip Borreliosis" for multiplex serologic analysis of mite-borne borreliosis demonstrated high diagnostic sensitivity and specificity. The percentage of detection of specific immunoglobulins was higher in "ImmunoChip Borreliosis" as compared with screening results in immune enzyme analysis. The high correlation between results of testing in immunochip and data of immune blotting is demonstrated to.

Publication types

English Abstract

MeSH terms

Animals
Antibodies, Bacterial / blood
Antibodies, Bacterial / immunology
Antibodies, Bacterial / isolation & purification
Borrelia burgdorferi / isolation & purification*
Borrelia burgdorferi / pathogenicity
Humans
Immunoglobulin G / blood
Immunoglobulin G / isolation & purification
Immunoglobulin M / blood
Immunoglobulin M / isolation & purification
Ixodes / microbiology*
Lyme Disease / blood
Lyme Disease / diagnosis*
Lyme Disease / immunology
Lyme Disease / microbiology*
Sensitivity and Specificity
Serologic Tests / methods

Substances

Antibodies, Bacterial
Immunoglobulin G
Immunoglobulin M