Abstract
FePt-Fe3O4 core-shell nanoparticles functionalized with 3,4-dihydroxyphenylacetic acid (DOPAC) and dimercaptosuccinic acid (DMSA) ligands were synthesized and characterized. We found that the DOPAC ligand enhances the magnetic properties of the FePt-Fe3O4 particles, in comparison with the DMSA ligand, which induces the oxidation of the shell layer that causes a significant reduction of the saturation magnetization. The synthesized magnetic nanoparticles were evaluated for applications in magnetic hyperthermia and magnetic resonance imaging contrast enhancement.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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3,4-Dihydroxyphenylacetic Acid / chemistry
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Biocompatible Materials
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Contrast Media / chemistry
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Ferric Compounds / chemistry*
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Iron / chemistry*
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Ligands
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Magnetic Resonance Imaging
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Magnetics
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Metal Nanoparticles / chemistry*
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Microscopy, Electron, Transmission
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Oxygen / chemistry
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Platinum / chemistry*
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Solubility
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Spectroscopy, Fourier Transform Infrared
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Succimer / chemistry
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Temperature
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Water / chemistry
Substances
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Biocompatible Materials
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Contrast Media
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Ferric Compounds
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Ligands
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Water
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3,4-Dihydroxyphenylacetic Acid
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ferric oxide
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Platinum
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Succimer
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Iron
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Oxygen