Abstract
Two cyclometalated Ir(III)-β-carboline complexes were identified as potent inducers of autophagic cell death. Autophagy induced by these complexes is ROS-mediated and caspase-independent.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemistry
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Autophagy / drug effects*
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Carbolines / chemistry*
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Cell Line
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Humans
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Iridium / chemistry*
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Ligands
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Organometallic Compounds / chemical synthesis
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Organometallic Compounds / chemistry*
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Organometallic Compounds / pharmacology*
Substances
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Alkaloids
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Carbolines
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Ligands
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Organometallic Compounds
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Iridium