Abstract
Peptide aptamers that specifically bind to the amino group on a solid-phase were screened by in vitro selection using the cDNA display method. The identified peptides have a unique structure containing two cyclic loops with disulphide bonds and a linkage region, which were indispensable for molecular recognition.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Aptamers, Peptide / chemistry*
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Aptamers, Peptide / metabolism*
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DNA, Complementary / genetics
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Disulfides / chemistry*
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Magnets / chemistry
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Microspheres
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Molecular Sequence Data
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Peptide Library*
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Peptides / chemical synthesis*
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Peptides / chemistry*
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Peptides / genetics
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Peptides / metabolism
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Polystyrenes / chemistry
Substances
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Aptamers, Peptide
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DNA, Complementary
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Disulfides
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Peptide Library
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Peptides
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Polystyrenes