The frequency of TP53 gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors

Br J Haematol. 2014 Aug;166(4):621-5. doi: 10.1111/bjh.12893. Epub 2014 Apr 12.
No abstract available

Keywords: TP53 mutations; chronic lymphocytic leukaemia; immunoglobulin genes; prognosis; stereotyped B cell receptors.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Gene Rearrangement, B-Lymphocyte / genetics
  • Genes, p53 / genetics*
  • Humans
  • Immunoglobulin Heavy Chains / genetics*
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Male
  • Middle Aged
  • Mutation / genetics*
  • Receptors, Antigen / genetics*

Substances

  • Immunoglobulin Heavy Chains
  • Receptors, Antigen