Plasma exchange significantly affects darunavir exposure

J Antimicrob Chemother. 2014 Aug;69(8):2296-7. doi: 10.1093/jac/dku108. Epub 2014 Apr 10.
No abstract available

Keywords: HIV protease inhibitors; apheresis; pharmacokinetics.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antiretroviral Therapy, Highly Active
  • CD4 Lymphocyte Count
  • Darunavir
  • Female
  • HIV Infections / blood
  • HIV Infections / drug therapy*
  • HIV Protease Inhibitors / blood
  • HIV Protease Inhibitors / pharmacokinetics
  • HIV Protease Inhibitors / therapeutic use*
  • HIV-1 / drug effects
  • Humans
  • Middle Aged
  • Plasma Exchange / adverse effects*
  • Ritonavir / therapeutic use
  • Sulfonamides / blood*
  • Sulfonamides / pharmacokinetics*
  • Sulfonamides / therapeutic use
  • Viral Load

Substances

  • HIV Protease Inhibitors
  • Sulfonamides
  • Ritonavir
  • Darunavir