Atypical fungal vertebral osteomyelitis in a tsunami survivor of the Great East Japan Earthquake

Spine (Phila Pa 1976). 2014 May 20;39(12):E739-42. doi: 10.1097/BRS.0000000000000317.

Abstract

Study design: Case report.

Objective: We report a rare case of fungal vertebral osteomyelitis in a tsunami survivor of the Great East Japan Earthquake.

Summary of background data: Fungal vertebral osteomyelitis due to Scedosporium apiospermum (S. apiospermum) is extremely rare. We describe the case of a 45-year-old male who developed vertebral osteomyelitis by S. apiospermum 1 month after near drowning in the huge tsunami after the Great East Japan Earthquake.

Methods: The patient was treated with a combination of percutaneous posterolateral endoscopic debridement and antifungal therapy. The case was evaluated with radiography and computed tomography, and his white blood cell count and C-reactive protein level in serum were measured 20 months after initiation of treatment.

Results: The patient had no low back pain and both white blood cell count and C-reactive protein had remained normal. Radiographs and computed tomography of lumbar spine demonstrated sclerotic change of endplates and spur formation bridging the L3 and L4 vertebral bodies.

Conclusion: We report a rare case of the fungal vertebral osteomyelitis caused by S. apiospermum. If a patient develops severe back pain after a near-drowning episode in dirty water such as a swamp or a river, the clinician should be suspicious of the possibility of fungal spondylitis by S. apiospermum.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Combined Modality Therapy
  • Debridement
  • Disasters
  • Earthquakes
  • Humans
  • Japan
  • Low Back Pain / etiology
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / microbiology
  • Lumbar Vertebrae / surgery
  • Lung Diseases, Fungal / complications
  • Male
  • Middle Aged
  • Mycoses / diagnosis*
  • Mycoses / drug therapy
  • Near Drowning / complications*
  • Osteomyelitis / diagnosis
  • Osteomyelitis / microbiology*
  • Osteomyelitis / therapy
  • Radiography
  • Scedosporium / isolation & purification*
  • Survivors
  • Tsunamis*
  • Water Microbiology

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents