Wnt signaling pathway, a potential target for Alzheimer's disease treatment, is activated by a novel multitarget compound ASS234

CNS Neurosci Ther. 2014 Jun;20(6):568-70. doi: 10.1111/cns.12269. Epub 2014 Apr 8.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Enzyme Inhibitors / pharmacology*
  • Gene Expression / drug effects*
  • Humans
  • Indoles / pharmacology*
  • Neuroblastoma / pathology
  • PPAR alpha / metabolism
  • Piperidines / pharmacology*
  • Wnt Signaling Pathway / drug effects*

Substances

  • Enzyme Inhibitors
  • Indoles
  • N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine
  • PPAR alpha
  • Piperidines