The complete mitochondrial genome of the orange-spotted spinefoot Siganus guttatus (Perciformes, Siganidae) is presented in this paper. The entire sequence, 16,505 bp in length, is comprised of 13 protein-coding genes, 22 tRNA genes, 2 rRNA genes and 1 control region. Structurally, the composition and order of genes are same as those found in other rabbitfishes. Except ND6 and 8 tRNA, all other mitochondrial genes were encoded on the heavy strand. Overall base compositions of mitogenome are 29.3% of A, 29.3% of C, 25.7% of T, and 15.7% of G, showing an obvious anti-G bias which was commonly found in fishes. Three conserved sequence blocks (CSB-1, CSB-2 and CSB-3) and long series of di- and mono-nucleotide microsatellite repeats in 3' end are observed in the putative control region. The complete mitogenome sequence of S. guttatus could provide useful information for further phylogenetic and population genetic studies.
Keywords: Mitochondrial genome; Siganidae; Siganus guttatus.