[Palmoplantar neutrophilic eccrine hidradenitis with general extension in a child in remission after acute lymphoblastic leukemia]

Ann Dermatol Venereol. 2014 Apr;141(4):285-9. doi: 10.1016/j.annder.2014.01.007. Epub 2014 Feb 25.
[Article in French]

Abstract

Background: Neutrophilic eccrine hidradenitis (NEH) is a form of neutrophilic dermatitis characterized by tender erythematous and painful papules involving the trunk, extremities and face. The generalized form is associated with malignant hemopathies. The palmoplantar form occurs in children without any context of malignancy. Histology shows a neutrophilic infiltrate surrounding and infiltrating the eccrine glands associated with vacuolar degeneration and necrosis of the epithelial secretory portion.

Patients and methods: We report the case of a 4-year-old girl with palmoplantar HEN progressing to the generalized form while in remission from acute lymphoblastic leukemia.

Discussion: Progression of HEN from the palmoplantar form to the generalized form has never been published previously in the literature.

Keywords: Acute lymphoblastic leukemia; Children; Eccrine hidradenitis; Enfant; Hidradénite eccrine; Leucémie lymphoblastique aiguë; Palmo-plantaire; Palmoplantar.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Biopsy
  • Child, Preschool
  • Diagnosis, Differential
  • Disease Progression
  • Female
  • Foot Dermatoses / pathology
  • Hand Dermatoses / pathology
  • Hidradenitis / chemically induced
  • Hidradenitis / pathology*
  • Humans
  • Immunocompromised Host*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
  • Remission Induction