Detecting Ni(II) in aqueous solution by 3-(2-pyridyl)-[1,2,3]triazolo[1,5-a]pyridine and dimethyl-β-cyclodextrin

Carbohydr Polym. 2014 Jul 17:107:124-31. doi: 10.1016/j.carbpol.2014.02.043. Epub 2014 Feb 22.

Abstract

A new supramolecular sensitizer for nickel(II) ion in aqueous solution based on a pyridyltriazolopyridine-cyclodextrin inclusion complex is proposed. The inclusion complexation behavior, characterization and binding ability of pyridyltriazolopyridine (PTP) with dimethyl-β-cyclodextrin (DMβCD) has been investigated both in solution and solid state by means of absorption, fluorescence, (1)H NMR, DSC, and molecular modeling methods. The stoichiometry of the inclusion complex is 1:1, and the thermodynamic studies indicate that the inclusion of PTP is mainly an entropic driven process. The 2D NMR studies revealed that the pyridyl-triazolopyridine is included by both sides of cyclodextrin which are in good agreement with the docking results. The fluorescence changes upon addition of divalent cations to the inclusion complex indicate a high selectivity and sensitivity for Ni(2+) by fluorescence quenching in neutral aqueous solution.

Keywords: Cyclodextrin; Fluorescence; Ni(II); Pyridyltriazolopyridine; Sensor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Environmental Monitoring
  • Models, Molecular
  • Molecular Conformation
  • Nickel / analysis*
  • Nickel / chemistry
  • Pyridines / chemistry*
  • Solutions
  • Triazoles / chemistry*
  • Water / chemistry*
  • Water Pollutants, Chemical / analysis*
  • Water Pollutants, Chemical / chemistry
  • beta-Cyclodextrins / chemistry*

Substances

  • 3-(2-pyridyl)-(1,2,3)triazolo(1,5-a)pyridine
  • Pyridines
  • Solutions
  • Triazoles
  • Water Pollutants, Chemical
  • beta-Cyclodextrins
  • Water
  • heptakis(2,6-O-dimethyl)beta-cyclodextrin
  • Nickel