Detection and differentiation of herpes simplex viruses by use of the viper platform: advantages, limitations, and concerns

J Clin Microbiol. 2014 Jun;52(6):2186-8. doi: 10.1128/JCM.03636-13. Epub 2014 Apr 2.

Abstract

The Viper HSV-Q(x) assay was evaluated for the detection of herpes simplex virus 1 (HSV-1) and HSV-2 in specimens from oral, anogenital, and other miscellaneous sites. The HSV-Q(x) assay was found to be highly sensitive and accurate; however, a gray zone may be required for specimens with values falling between 50 and 800 maximum relative fluorescence units.

Publication types

  • Evaluation Study

MeSH terms

  • Fluorescence
  • Genitalia / virology
  • Herpes Genitalis / diagnosis*
  • Herpes Genitalis / virology*
  • Herpes Simplex / diagnosis*
  • Herpes Simplex / virology*
  • Humans
  • Molecular Diagnostic Techniques / methods*
  • Molecular Diagnostic Techniques / standards
  • Mouth / virology
  • Sensitivity and Specificity
  • Simplexvirus / classification*
  • Simplexvirus / isolation & purification*