Bioresorbable metal scaffold for cardiovascular application: current knowledge and future perspectives

Cardiovasc Revasc Med. 2014 Mar;15(2):109-16. doi: 10.1016/j.carrev.2014.01.011. Epub 2014 Jan 30.

Abstract

Over the last decade, the introduction of drug-eluting stents has dramatically reduced restenosis and the need for repeat revascularization after implantation of metallic stents. Numerous concerns still remain, however, because of their permanent nature. Thus, the concept of bioresorbable temporary scaffolds composed of biocompatible materials has emerged as a potential alternative to permanent metal stents. Here we focus on metal alloys & discuss preclinical and clinical experiences with bioresorbable metal scaffolds.

Keywords: Bioresorbable metal scaffold; Iron; Magnesium; Stent.

Publication types

  • Review

MeSH terms

  • Absorbable Implants*
  • Animals
  • Coronary Artery Disease / diagnosis
  • Coronary Artery Disease / therapy*
  • Drug-Eluting Stents
  • Endovascular Procedures / adverse effects
  • Endovascular Procedures / instrumentation*
  • Humans
  • Metals
  • Percutaneous Coronary Intervention / adverse effects
  • Percutaneous Coronary Intervention / instrumentation*
  • Peripheral Arterial Disease / diagnosis
  • Peripheral Arterial Disease / therapy*
  • Prosthesis Design
  • Stents*
  • Tissue Scaffolds*
  • Treatment Outcome

Substances

  • Metals