Infective dermatitis associated with HTLV-1 mimics common eczemas in children and may be a prelude to severe systemic diseases

Abstract

Infective dermatitis associated with human T-cell lymphotropic virus type 1 (HTLV-1) (IDH) is a chronic dermatitis that has been observed in a variable proportion of HTLV-1-infected children. IDH may serve as an early clinical marker for HTLV-1 infection and an indicator of increased risk for developing other HTLV-1-associated conditions. Factors that lead only some infected children to develop IDH are poorly understood. The variable clinical presentation of IDH, in particular its chronicity, the morphology and distribution of the lesions, and its clinical resemblance to other cutaneous inflammatory conditions, make it necessary to distinguish it from other common dermatoses.

Keywords: Adult T cell leukemia/lymphoma (ATLL); Atopic dermatitis; HTLV-1 infection; Infective dermatitis; Seborrhoeic dermatitis.