Xylaolide A, a new lactone from the fungus Xylariaceae sp. DPZ-SY43

Bin Yang; Junde Dong; Xiuping Lin; Huaming Tao; Xuefeng Zhou; Yonghong Liu

doi:10.1080/14786419.2014.901318

Xylaolide A, a new lactone from the fungus Xylariaceae sp. DPZ-SY43

Nat Prod Res. 2014;28(13):967-70. doi: 10.1080/14786419.2014.901318. Epub 2014 Mar 28.

Authors

Bin Yang¹, Junde Dong, Xiuping Lin, Huaming Tao, Xuefeng Zhou, Yonghong Liu

Affiliation

¹ a CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica/Research Center for Marine Microbes, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou 510301 , P.R. China.

PMID: 24673400
DOI: 10.1080/14786419.2014.901318

Abstract

Chemical investigation of the fungus Xylariaceae sp. DPZ-SY43 has led to the isolation of a new compound, xylaolide A (1) together with three known compounds (2-4). The structures were established by analysing the spectroscopic data. Compound 1 was evaluated for its cytotoxicity.

Keywords: Xylariaceae sp.; cytotoxicity; lactone; xylaolide A.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents / chemistry
Antineoplastic Agents / isolation & purification*
Antineoplastic Agents / pharmacology
Drug Screening Assays, Antitumor
HL-60 Cells
HeLa Cells
Humans
K562 Cells
Lactones / chemistry
Lactones / isolation & purification*
Lactones / pharmacology
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Xylariales / chemistry*

Substances

Antineoplastic Agents
Lactones
xylaolide A