Redox-triggered changes in the self-assembly of a ferrocene-peptide conjugate

Chem Commun (Camb). 2014 May 30;50(42):5551-3. doi: 10.1039/c3cc49268k.

Abstract

Ultrasonication of a ferrocene conjugate of a short amyloid peptide (Aβ18-20) in toluene causes formation of an organogel, which undergoes dramatic structural changes upon oxidation from a nanofibrillar network to spherical micelles. This morphological change is redox-controlled and reversible.

MeSH terms

  • Amino Acid Sequence
  • Amyloid beta-Peptides / chemistry*
  • Ferrous Compounds / chemistry*
  • Hydrophobic and Hydrophilic Interactions
  • Metallocenes
  • Micelles
  • Nanostructures / chemistry
  • Oligopeptides / chemistry*
  • Oxidation-Reduction

Substances

  • Amyloid beta-Peptides
  • Ferrous Compounds
  • Metallocenes
  • Micelles
  • Oligopeptides
  • ferrocene