Contribution of CD39 to the immunosuppressive microenvironment of acute myeloid leukaemia at diagnosis

Br J Haematol. 2014 Jun;165(5):722-5. doi: 10.1111/bjh.12774. Epub 2014 Feb 12.

Authors

Nicolas Dulphy¹, Guylaine Henry, Patrice Hemon, Zena Khaznadar, Hervé Dombret, Nicolas Boissel, Armand Bensussan, Antoine Toubert

Affiliation

¹ Institut Universitaire d'Hématologie, Sorbonne Paris Cité, Univ Paris Diderot, Paris, France; Department of Immunology and Histocompatibility, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, Paris, France; UMR-S940, Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France. nicolas.dulphy@univ-paris-diderot.fr.

PMID: 24666252
DOI: 10.1111/bjh.12774

No abstract available

Keywords: Acute myeloid leukaemia; CD39; CD73; immunosuppressive environment; regulatory T-cell.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antigens, CD / immunology*
Apyrase / immunology*
Humans
Immune Tolerance / immunology
Immunophenotyping
Leukemia, Myeloid, Acute / immunology*
Tumor Microenvironment / immunology*

Substances

Antigens, CD
Apyrase
CD39 antigen