Bilateral juvenile nasopharyngeal angiofibroma: report of a case

Int Forum Allergy Rhinol. 2014 Jul;4(7):603-6. doi: 10.1002/alr.21322. Epub 2014 Mar 24.

Abstract

Background: Juvenile nasopharyngeal angiofibroma (JNA) is the most common benign neoplasm of the nasopharynx. Almost always unilateral on diagnosis, JNAs are locally invasive and may extend across the midline, giving a false bilateral appearance; as such, true bilateral JNA is exceedingly rare. We present a recent case of true bilateral JNA.

Methods: Single case report of a patient with bilateral JNA, including clinical presentation, diagnosis, and management.

Results: The patient presented with unilateral nasal obstruction and recurrent epistaxis. Computed tomography and magnetic resonance imaging demonstrated bilateral, noncontiguous masses. Angiography revealed independent vascular supplies from each respective side with no bilateral supply noted. The patient underwent preoperative embolization followed by endoscopic surgical removal of the larger mass; no complications were noted. Follow-up at 2 years demonstrated no recurrence or growth.

Conclusion: The vast majority of JNAs are unilateral, though invasive growth to the contralateral side may appear "bilateral" in presentation. Proper identification of true bilateral JNA is helpful in guiding management, wherein excision of both tumors may not be necessary.

Keywords: angiofibroma; bilateral; epistaxis; imaging; radiology.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Angiofibroma / diagnosis*
  • Angiofibroma / surgery
  • Early Detection of Cancer
  • Endoscopy*
  • Epistaxis / diagnosis*
  • Epistaxis / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Nasal Obstruction / diagnosis*
  • Nasal Obstruction / surgery
  • Nasopharyngeal Neoplasms / diagnosis*
  • Nasopharyngeal Neoplasms / surgery
  • Nose / pathology
  • Nose / surgery
  • Pharynx / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome