Abstract
The therapeutic applications of many anticancer or antimicrobial metal complexes often suffer from low solubility and low stability in physiological conditions or from drug resistance. To circumvent these problems, nanoparticle systems that allow controlled release and specific accumulation in the targeted disease tissue are of advantage for efficient treatment with minimal toxicity. The focus of this Research News is metal-based nanomaterials comprising anticancer gold(III)/platinum(II) complexes or antimicrobial silver, highlighting the controlled-release properties of self-assembled metal systems.
Keywords:
anticancer; antimicrobial materials; gold/platinum/silver; nanoparticles.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Animals
-
Anti-Infective Agents / administration & dosage*
-
Anti-Infective Agents / chemistry
-
Antineoplastic Agents / administration & dosage*
-
Antineoplastic Agents / chemistry
-
Delayed-Action Preparations / administration & dosage*
-
Delayed-Action Preparations / chemistry
-
Gold Compounds / administration & dosage
-
Gold Compounds / chemistry
-
Humans
-
Metal Nanoparticles / administration & dosage*
-
Metal Nanoparticles / chemistry
-
Nanomedicine / instrumentation
-
Nanomedicine / methods*
-
Platinum Compounds / administration & dosage
-
Platinum Compounds / chemistry
-
Silver Compounds / administration & dosage
-
Silver Compounds / chemistry
Substances
-
Anti-Infective Agents
-
Antineoplastic Agents
-
Delayed-Action Preparations
-
Gold Compounds
-
Platinum Compounds
-
Silver Compounds