State of the art Raman techniques for biological applications

Alasdair Rae; Rainer Stosch; Petr Klapetek; Angela R Hight Walker; Debdulal Roy

doi:10.1016/j.ymeth.2014.02.035

State of the art Raman techniques for biological applications

Methods. 2014 Jul 1;68(2):338-47. doi: 10.1016/j.ymeth.2014.02.035. Epub 2014 Mar 21.

Authors

Alasdair Rae¹, Rainer Stosch², Petr Klapetek³, Angela R Hight Walker⁴, Debdulal Roy⁵

Affiliations

¹ National Physical Laboratory (NPL), Hampton Road, Teddington, Middlesex TW11 0LW, United Kingdom.
² Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, Germany.
³ Czech Metrology Institute (CMI), Okruzni 31, Brno 638 00, Czech Republic.
⁴ National Institute of Science and Technology (NIST), 100 Bureau Drive, Gaithersburg, MD 20899-1070, United States.
⁵ National Physical Laboratory (NPL), Hampton Road, Teddington, Middlesex TW11 0LW, United Kingdom. Electronic address: debdulal.roy@npl.co.uk.

PMID: 24662479
DOI: 10.1016/j.ymeth.2014.02.035

Abstract

Raman spectroscopy is a powerful tool for the elucidation of qualitative and quantitative information from biological systems and has huge potential in areas such as biotechnologies, drug discovery, agro-chemical research and clinical diagnostics. This report summarises the principal Raman techniques applied to biomedical systems and discusses the challenges that exist to the wide spread adoption of Raman spectroscopy.

Keywords: Biomedical; Nonlinear optics; Quantification; Raman spectroscopy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Humans
Nonlinear Dynamics
Optics and Photonics*
Spectrum Analysis, Raman / methods*