Postsurgical contact dermatitis due to povidone iodine: a diagnostic dilemma

Actas Dermosifiliogr. 2014 Apr;105(3):300-4. doi: 10.1016/j.adengl.2012.11.028. Epub 2014 Mar 21.

Abstract

We present 7 cases of postsurgical contact dermatitis due to povidone iodine. The diagnosis was based on the clinical manifestations, the history of exposure, the site of the lesions, and the results of patch tests. This type of dermatitis can develop in the area of surgery or at distant sites exposed to povidone iodine during the surgical intervention. Patch tests with 10% povidone iodine in petrolatum were positive in all patients. Based on the results of the same tests in a control group, we recommend the use of petrolatum rather than water as the vehicle for the diagnosis of this form of contact dermatitis. Repeated open application tests with a commercially available solution of povidone iodine were negative. We conclude that the presence of the solution under occlusion during surgery is necessary both for the symptoms to develop and for the diagnosis to be made. This condition may be underdiagnosed.

Keywords: Antiseptics; Antisépticos; Cirugía; Contact dermatitis; Dermatitis de contacto; Patch tests; Povidona iodada; Povidone iodine; Prueba abierta repetida; Pruebas epicutáneas; Repeated open application test; Surgery.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Anti-Infective Agents, Local / adverse effects*
  • Dermatitis, Contact / diagnosis*
  • Dermatitis, Contact / etiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patch Tests
  • Postoperative Complications / chemically induced*
  • Postoperative Complications / diagnosis*
  • Povidone-Iodine / adverse effects*

Substances

  • Anti-Infective Agents, Local
  • Povidone-Iodine