A phase II trial of pan-KIR2D blockade with IPH2101 in smoldering multiple myeloma

Haematologica. 2014 Jun;99(6):e81-3. doi: 10.3324/haematol.2013.103085. Epub 2014 Mar 21.
No abstract available

Keywords: HLA-C binding KIR2D reports; IPH2101; KIR2D blockade; NK-cell function; clinical response; smoldering multiple myeloma.

Publication types

  • Clinical Trial, Phase II
  • Letter

MeSH terms

  • Antibodies, Monoclonal / pharmacology*
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Humans
  • Multiple Myeloma / diagnosis*
  • Multiple Myeloma / drug therapy*
  • Receptors, KIR / antagonists & inhibitors*
  • Treatment Outcome

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Antineoplastic Agents
  • Receptors, KIR
  • IPH-2101

Associated data

  • ClinicalTrials.gov/NCT01248455