Acute stress rapidly increases the readily releasable pool of glutamate vesicles in prefrontal and frontal cortex through non-genomic action of corticosterone

G Treccani; L Musazzi; C Perego; M Milanese; N Nava; T Bonifacino; J Lamanna; A Malgaroli; F Drago; G Racagni; J R Nyengaard; G Wegener; G Bonanno; M Popoli

doi:10.1038/mp.2014.20

Acute stress rapidly increases the readily releasable pool of glutamate vesicles in prefrontal and frontal cortex through non-genomic action of corticosterone

Mol Psychiatry. 2014 Apr;19(4):401. doi: 10.1038/mp.2014.20.

Authors

G Treccani¹, L Musazzi¹, C Perego², M Milanese³, N Nava⁴, T Bonifacino³, J Lamanna⁵, A Malgaroli⁵, F Drago⁶, G Racagni⁷, J R Nyengaard⁸, G Wegener⁹, G Bonanno³, M Popoli¹

Affiliations

¹ Laboratory of Neuropsychopharmacology and Functional Neurogenomics, Dipartimento di Scienze Farmacologiche e Biomolecolari and CEND, Università di Milano, Milano, Italy.
² Laboratory of Cell Physiology, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milano, Italy.
³ Unit of Pharmacology and Toxicology, Center of Excellence for Biomedical Research, Department of Pharmacy, Università di Genova, Genova, Italy.
⁴ 1] Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced Bioimaging, Aarhus University Hospital, Aarhus C, Denmark [2] Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Denmark.
⁵ Neurobiology of Learning Unit, Scientific Institute San Raffaele and Università Vita e Salute San Raffaele, Milano, Italy.
⁶ Section of Pharmacology and Biochemistry, Department of Clinical and Molecular Biomedicine, Università di Catania, Catania, Italy.
⁷ 1] Laboratory of Neuropsychopharmacology and Functional Neurogenomics, Dipartimento di Scienze Farmacologiche e Biomolecolari and CEND, Università di Milano, Milano, Italy [2] I.R.C.C.S San Giovanni di Dio-Fatebenefratelli, Brescia, Italy.
⁸ Stereology and Electron Microscopy Laboratory, Centre for Stochastic Geometry and Advanced Bioimaging, Aarhus University Hospital, Aarhus C, Denmark.
⁹ 1] Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Denmark [2] Pharmaceutical Research Center of Excellence, School of Pharmacy (Pharmacology), North-West University, Potchefstroom, South Africa.

PMID: 24658610
DOI: 10.1038/mp.2014.20

No abstract available

MeSH terms

Animals
Corticosterone / metabolism*
Corticosterone / pharmacology
Frontal Lobe / pathology*
Glutamic Acid / metabolism*
In Vitro Techniques
Presynaptic Terminals / drug effects
Presynaptic Terminals / metabolism*
Stress, Psychological / metabolism*
Stress, Psychological / pathology*

Substances

Glutamic Acid
Corticosterone