The light touch of delta opioid receptors

Wendy Imlach; Macdonald J Christie

doi:10.1016/j.neuron.2014.03.004

The light touch of delta opioid receptors

Neuron. 2014 Mar 19;81(6):1220-1222. doi: 10.1016/j.neuron.2014.03.004.

Authors

Wendy Imlach¹, Macdonald J Christie²

Affiliations

¹ Discipline of Pharmacology, The University of Sydney, Sydney, NSW 2006, Australia.
² Discipline of Pharmacology, The University of Sydney, Sydney, NSW 2006, Australia. Electronic address: mac.christie@sydney.edu.au.

PMID: 24656246
DOI: 10.1016/j.neuron.2014.03.004

Abstract

Expression of δ-opioid receptors in sensory neurons is controversial. In this issue of Neuron, Bardoni et al. (2014) present evidence that DOPrs are expressed on mechanosensory neurons involved in detecting nonnoxious touch but are very sparse in μ-opioid receptor-rich nociceptive neurons.

Publication types

Comment

MeSH terms

Animals
Mechanoreceptors / physiology*
Neurons / physiology*
Nociceptors / physiology*
Receptors, Opioid, delta / metabolism*
Spinal Cord / metabolism*

Substances

Receptors, Opioid, delta