A novel method to detect causative mutations in fibrinogen, using a small amount of blood processed through HPLC and time of flight (TOF) mass spectrometry

MeSH terms

• Afibrinogenemia / congenital*
• Afibrinogenemia / diagnosis
• Chromatography, High Pressure Liquid / methods*
• Fibrinogen / analysis*
• Hemorrhage / diagnosis*
• Humans
• Male
• Plasma / chemistry*
• Spectrometry, Mass, Electrospray Ionization / methods*