Suilysin remodels the cytoskeletons of human brain microvascular endothelial cells by activating RhoA and Rac1 GTPase

Protein Cell. 2014 Apr;5(4):261-4. doi: 10.1007/s13238-014-0037-0.

Authors

Qingyu Lv¹, Huaijie Hao, Lili Bi, Yuling Zheng, Xuyu Zhou, Yongqiang Jiang

Affiliation

¹ State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Brain
Cholesterol / chemistry
Cytoskeleton / drug effects
Endothelial Cells / cytology
Endothelial Cells / metabolism
Hemolysin Proteins / chemistry
Hemolysin Proteins / pharmacology
Humans
Phalloidine / pharmacology
Pseudopodia / drug effects
Stress Fibers / drug effects
rac1 GTP-Binding Protein / metabolism*
rhoA GTP-Binding Protein / metabolism*

Substances

Hemolysin Proteins
suilysin
Phalloidine
Cholesterol
rac1 GTP-Binding Protein
rhoA GTP-Binding Protein