An introduction to RNA databases

Methods Mol Biol. 2014:1097:107-23. doi: 10.1007/978-1-62703-709-9_6.

Abstract

We present an introduction to RNA databases. The history and technology behind RNA databases are briefly discussed. We examine differing methods of data collection and curation and discuss their impact on both the scope and accuracy of the resulting databases. Finally, we demonstrate these principles through detailed examination of four leading RNA databases: Noncode, miRBase, Rfam, and SILVA.

Publication types

  • Review

MeSH terms

  • Computational Biology / methods*
  • Databases, Nucleic Acid*
  • RNA / chemistry*
  • RNA / genetics

Substances

  • RNA