Diffusion model for ultrasound-modulated light

J Biomed Opt. 2014 Mar;19(3):35005. doi: 10.1117/1.JBO.19.3.035005.

Abstract

Researchers use ultrasound (US) to modulate diffusive light in a highly scattering medium like tissue. This paper analyzes the US-optical interaction in the scattering medium and derives an expression for the US-modulated optical radiance. The diffusion approximation to the radiative transport equation is employed to develop a Green's function for US-modulated light. The predicted modulated fluence and flux are verified using finite-difference time-domain simulations. The Green's function is then utilized to illustrate the modulated reflectance as the US-optical interaction increases in depth. The intent of this paper is to focus on high US frequencies necessary for high-resolution imaging because they are of interest for applications such as phase conjugation.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Computer Simulation
  • Diffusion*
  • Light*
  • Models, Theoretical*
  • Phantoms, Imaging
  • Scattering, Radiation*
  • Ultrasonics*