Uniparental Trisomy of a Mutated HRAS Proto-Oncogene in Embryonal Rhabdomyosarcoma of a Patient With Costello Syndrome

MeSH terms

• Abdominal Neoplasms / chemistry
• Abdominal Neoplasms / diagnosis
• Abdominal Neoplasms / genetics*
• Abdominal Neoplasms / pathology
• Abdominal Neoplasms / surgery
• Biomarkers, Tumor / genetics*
• Chemotherapy, Adjuvant
• Child, Preschool
• Chromosomes, Human, Pair 11*
• Costello Syndrome / diagnosis
• Costello Syndrome / genetics*
• DNA Mutational Analysis
• Female
• Genetic Predisposition to Disease
• Genetic Testing / methods
• Heredity
• Heterozygote
• Humans
• Immunohistochemistry
• Magnetic Resonance Imaging
• Mutation*
• Neoplasm Grading
• Pedigree
• Phenotype
• Predictive Value of Tests
• Proto-Oncogene Mas
• Proto-Oncogene Proteins p21(ras) / genetics*
• Rhabdomyosarcoma, Embryonal / chemistry
• Rhabdomyosarcoma, Embryonal / diagnosis
• Rhabdomyosarcoma, Embryonal / genetics*
• Rhabdomyosarcoma, Embryonal / pathology
• Rhabdomyosarcoma, Embryonal / surgery
• Treatment Outcome
• Trisomy*