Abstract
This review provides up-to-date information on the anticancer properties of Monascus-fermented products. Topics covered include clinical evidence for the anticancer potential of Monascus metabolites, bioactive Monascus components with anticancer potential, mechanisms of the anticancer effects of Monascus metabolites, and existing problems as well as future perspectives. With the advancement of related fields, the development of novel anticancer Monascus food products and/or pharmaceuticals will be possible with the ultimate goal of decreasing the incidence and mortality of malignancies in humans.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Antineoplastic Agents / pharmacology
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Antineoplastic Agents / therapeutic use*
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Apoptosis / drug effects
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Autophagy / drug effects
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Biological Products / pharmacology
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Biological Products / therapeutic use*
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Cell Movement / drug effects
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Fermentation
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Humans
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Monascus / metabolism*
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Neoplasm Invasiveness / prevention & control
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Neoplasm Metastasis
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Neoplasms / blood supply
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Neoplasms / drug therapy*
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Neoplasms / pathology
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Radiation Tolerance / drug effects
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Radiation-Sensitizing Agents / pharmacology
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Radiation-Sensitizing Agents / therapeutic use
Substances
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Antineoplastic Agents
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Biological Products
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Radiation-Sensitizing Agents