Reliability of solar keratosis clinical diagnosis: A prospective study

Australas J Dermatol. 2015 May;56(2):e49-52. doi: 10.1111/ajd.12095. Epub 2014 Mar 17.

Abstract

Usually solar keratoses (SK) are diagnosed clinically. However other diseases may clinically present as erythematous macules, papules or patches on sun-exposed areas; therefore the histopathology remains the gold standard diagnostic tool. Our study, which assessed the efficacy of photodynamic therapy (PDT), showed that one in 20 clinically diagnosed SK lesions grade I-II identified by board-certified dermatologists were rosacea and only one in 40 were malignant lesions. These findings should be considered by clinicians who treat clinically diagnosed grade I-II SK without response to treatment or diagnose the recurrence of SK after PDT.

Keywords: clinic; histopathology; solar keratosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diagnostic Errors
  • Humans
  • Keratosis, Actinic / diagnosis*
  • Keratosis, Actinic / drug therapy*
  • Keratosis, Actinic / pathology
  • Middle Aged
  • Photochemotherapy*
  • Prospective Studies
  • Rosacea / pathology
  • Skin Neoplasms / pathology*