Early diagnosis of hepatic intravascular lymphoma: a case report and literature review

Intern Med. 2014;53(6):587-93. doi: 10.2169/internalmedicine.53.1812.

Abstract

Hepatic intravascular large B-cell lymphoma (IVL) is a rare disease entity that involves invasion into various organs. Due to the aggressive behavior and poor prognosis of the disease and the difficulty in making an early diagnosis, some cases are diagnosed at autopsy. Early suspicion and the use of imaging studies and liver biopsies are key for diagnosing IVL; however, no reports have described the results of imaging studies due to the limited number of cases. We herein report the results of imaging studies of hepatic IVL, including the findings PET-CT, dynamic-CT, EOB-MRI and CEUS. These results may help physicians to make an early diagnosis and improve the prognosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Early Diagnosis
  • Female
  • Humans
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / pathology
  • Lymphoma, Large B-Cell, Diffuse / diagnosis*
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Lymphoma, Large B-Cell, Diffuse / pathology
  • Magnetic Resonance Imaging
  • Positron-Emission Tomography
  • Prednisolone / administration & dosage
  • Prognosis
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vascular Neoplasms / diagnosis*
  • Vascular Neoplasms / drug therapy
  • Vascular Neoplasms / pathology
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisolone

Supplementary concepts

  • VAP-cyclo protocol