Abstract
Metasequoia glyptostroboides, a tree native to China, is described as a living fossil and has existed for millions of years. The oldest fossils recorded have been dated to the late Cretaceous era. During the time of its existence, the molecular defence system of the tree has apparently resisted millions of generations of pathogens, which encouraged search for novel natural product from this source. Eight compounds have been characterised from needles of M. glyptostroboides, including the novel natural product 6-carboxydihydroresveratrol 3-O-β-glucopyranoside. The structure determinations were based on extensive use of 2D NMR spectroscopic techniques and high-resolution mass spectrometry.
Keywords:
2D NMR; 6-Carboxydihydroresveratrol 3-glucoside; Bibenzyl; Metasequoia glyptostroboides.
Copyright © 2014 Elsevier B.V. All rights reserved.
MeSH terms
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Biological Assay
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Biological Products
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Biphenyl Compounds / pharmacology
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Cupressaceae / chemistry*
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Free Radical Scavengers / chemistry*
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Free Radical Scavengers / isolation & purification
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Free Radical Scavengers / pharmacology
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Glucosides / chemistry*
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Glucosides / isolation & purification
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Glucosides / pharmacology
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Lipoxygenase Inhibitors / chemistry*
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Lipoxygenase Inhibitors / isolation & purification
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Lipoxygenase Inhibitors / pharmacology
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Molecular Structure
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Picrates / pharmacology
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Plant Leaves / chemistry
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Plants, Medicinal
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Stilbenes / chemistry*
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Stilbenes / isolation & purification
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Stilbenes / pharmacology
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Trees
Substances
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6-carboxydihydroresveratrol 3-O-beta-glucopyranoside
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Biological Products
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Biphenyl Compounds
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Free Radical Scavengers
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Glucosides
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Lipoxygenase Inhibitors
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Picrates
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Stilbenes
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dihydroresveratrol
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1,1-diphenyl-2-picrylhydrazyl