Different paths to pathogenesis

Trends Microbiol. 2014 Apr;22(4):168-9. doi: 10.1016/j.tim.2014.02.013. Epub 2014 Mar 12.

Abstract

In a recent issue of Cell Host & Microbe, Elsen and colleagues identify a novel hemolysin in a highly virulent Pseudomonas aeruginosa strain that lacks a type III secretion system. Their analysis provides another example of how individual strains of P. aeruginosa utilize different virulence mechanisms to cause severe infections.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Hemorrhage / etiology*
  • Humans
  • Lung / pathology*
  • Membrane Transport Proteins / metabolism*
  • Pneumonia, Bacterial / microbiology*
  • Pore Forming Cytotoxic Proteins / metabolism*
  • Pseudomonas aeruginosa / pathogenicity*
  • Pseudomonas aeruginosa / physiology*

Substances

  • Membrane Transport Proteins
  • Pore Forming Cytotoxic Proteins