Gold-catalyzed 6-exo-dig cycloisomerization: a versatile approach to functionalized phenanthrenes

Chao Shu; Long Li; Cheng-Bin Chen; Hong-Cheng Shen; Long-Wu Ye

doi:10.1002/asia.201400034

Gold-catalyzed 6-exo-dig cycloisomerization: a versatile approach to functionalized phenanthrenes

Chem Asian J. 2014 Jun;9(6):1525-9. doi: 10.1002/asia.201400034. Epub 2014 Mar 12.

Authors

Chao Shu¹, Long Li, Cheng-Bin Chen, Hong-Cheng Shen, Long-Wu Ye

Affiliation

¹ State Key Laboratory for Physical Chemistry of Solid Surfaces, The Key Laboratory for Chemical Biology of Fujian Province and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian 361005 (P.R. China), Fax: (+86) 592-218-5833.

PMID: 24623555
DOI: 10.1002/asia.201400034

Abstract

A novel gold-catalyzed 6-exo-dig cycloisomerization of o-propargylbiaryls has been developed that provides ready access to functionalized phenanthrenes in largely good to excellent yields. Notable features of this method are readily available starting materials, mild reaction conditions, and broad substrate scope.

Keywords: cycloisomerization; gold; homogeneous catalysis; hydroarylation; phenanthrenes.