Auger-architectomics: introducing a new nanotechnology to infectious disease

Chantel W Swart; Carolina H Pohl; Johan L F Kock

doi:10.1007/978-81-322-1777-0_1

Auger-architectomics: introducing a new nanotechnology to infectious disease

Adv Exp Med Biol. 2014:807:1-8. doi: 10.1007/978-81-322-1777-0_1.

Authors

Chantel W Swart¹, Carolina H Pohl, Johan L F Kock

Affiliation

¹ Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, Bloemfontein, Free State, South Africa.

PMID: 24619614
DOI: 10.1007/978-81-322-1777-0_1

Abstract

In 2010, we developed a new imaging nanotechnology called Auger-architectomics, to study drug biosensors in nano-detail. We succeeded in applying Auger atom electron physics coupled to scanning electron microscopy (SEM) and Argon-etching to cell structure exploration, thereby exposing a new dimension in structure and element composition architecture. Auger-architectomics was used to expose the fate and effect of drugs on cells. This technology should now be expanded to diseased cells. This paper will outline the development, proof of concept, and application of this imaging nanotechnology. A virtual tour is available at: http://vimeo.com/user6296337 .

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Biosensing Techniques / instrumentation
Biosensing Techniques / methods*
Communicable Diseases / diagnosis*
Humans
Microscopy, Electron, Scanning / methods*
Nanotechnology / instrumentation
Nanotechnology / methods*