Deep sequencing identifies IDH1 R132S mutation in adult medulloblastoma

J Clin Oncol. 2015 Feb 20;33(6):e27-31. doi: 10.1200/JCO.2013.49.4864. Epub 2014 Mar 10.

Authors

Matija Snuderl¹, Joanna Triscott², Paul A Northcott³, Helen A Shih⁴, Esther Kong², Hayley Robinson⁴, Sandra E Dunn², A John Iafrate⁴, Stephen Yip⁵

Affiliations

¹ New York University Langone Medical Center and Medical School, New York, NY.
² University of British Columbia, Vancouver, British Columbia, Canada.
³ German Cancer Research Center, Heidelberg, Germany.
⁴ Massachusetts General Hospital and Harvard Medical School, Boston, MA.
⁵ University of British Columbia, Vancouver, British Columbia, Canada SYip@bccancer.bc.ca.

No abstract available

Publication types

Case Reports
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Cerebellar Neoplasms / genetics*
Female
Humans
Isocitrate Dehydrogenase / genetics*
Medulloblastoma / genetics*
Middle Aged
Mutation*

Substances

Isocitrate Dehydrogenase
IDH1 protein, human

Grants and funding