In vivo biocompatibility versus degree of conversion of resin-reinforced cements in different time periods

Microsc Res Tech. 2014 May;77(5):335-40. doi: 10.1002/jemt.22348. Epub 2014 Feb 25.

Abstract

This study focused on test the null hypothesis that there is no difference between the degree of conversion and biocompatibility of different resin reinforced glass ionomer cements (RRGICs). Forty-eight male Wistar rats were used, distributed into four groups (n = 12), as follows: Group C (Control, polyethylene), Group FOB (Fuji Ortho Band), Group UBL (Ultra band Lok), and Group MCG (Multicure Glass), in subcutaneous tissue. The events of edema, necrosis, granulation tissue, multinuclear giant cells, young fibroblasts, and collagen formation were analyzed at 7, 15, and 30 days. The degree of conversion was evaluated by the Fourier method. Biocompatibility and degree of conversion were assessed using the Kruskal-Wallis and Dunn tests, and ANOVA and Tukey's test, respectively (P < 0.05). It was observed that, there was significant difference between Groups FOB and UBL for the presence of young fibroblasts at 15 days (P = 0.034) and between the Control and MCG Groups for the presence of multinucleated giant cells at 30 days (P = 0.009). Monomer conversion increased progressively until day 30, with significant difference between Group FOB and Groups UBL and MCG (P = 0.013) at 15 days. The null hypothesis was partially accepted, Fuji Ortho Band showed a less monomer conversion and a smaller number of young fibroblasts in the time of 15 days.

Keywords: biocompatibility; glass ionomer cements; orthodontics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrylic Resins / adverse effects
  • Acrylic Resins / metabolism
  • Aluminum Silicates / adverse effects
  • Aluminum Silicates / metabolism
  • Animals
  • Edema / chemically induced
  • Fibroblasts / metabolism
  • Giant Cells / metabolism
  • Glass Ionomer Cements / adverse effects
  • Glass Ionomer Cements / metabolism*
  • Inflammation / chemically induced
  • Male
  • Materials Testing / methods
  • Necrosis / chemically induced
  • Rats, Wistar
  • Resin Cements / adverse effects
  • Resin Cements / metabolism*
  • Time Factors

Substances

  • Acrylic Resins
  • Aluminum Silicates
  • Fuji Ortho
  • Glass Ionomer Cements
  • Resin Cements
  • Ultra Band-Lok