Dependence of DNA condensation on the correlation distance between condensed counterions

J Biol Phys. 2012 Sep;38(4):589-96. doi: 10.1007/s10867-012-9273-9. Epub 2012 Aug 3.

Abstract

Based on the ground state of counterions condensed on a DNA molecule, a model has been developed to successfully detect the process of DNA condensation. Through further investigation, the process of DNA condensation strongly depends on the correlation distance between condensed counterions on DNA molecules. Generally, there are two routes. The process of DNA condensation with the correlation distance between condensed counterions being 2 nm or 4 nm is different from the one with the correlation distance between condensed counterions being 3 nm or 5 nm. Effects of ionic strength on the diameter of toroidal condensates originate from the increase of correlation distance between condensed counterions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry*
  • Models, Molecular*
  • Nucleic Acid Conformation

Substances

  • DNA