Shared decision-making in treatment of Merkel cell carcinoma

BMJ Case Rep. 2014 Mar 10:2014:bcr2013201675. doi: 10.1136/bcr-2013-201675.

Abstract

An 82-year-old woman presented with an asymptomatic mass, rapidly growing on her left cheek for the previous 3 months. Punch biopsy of the tumour was performed, and the pathology was compatible with Merkel cell carcinoma. A resection margin of more than 1 cm would involve left oral commissura, potentially damaging speech, eating and drinking ability. The patient had a strong wish of keeping surgery simple in order to maintain quality of life. Tumour excision was performed with 1 cm resection margin, and postoperatively the patient was referred to adjuvant radiation therapy. Sensibility of upper and lower lip remained unaffected, while motor innervation of left upper lip was impaired. Despite this, the patient's ability to talk and eat was unaffected. Surgery, with adjunctive radiation therapy, is the first-line of treatment for the primary tumour. The option for a more conservative treatment is not first choice, but can be considered upon individual assessment.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Carcinoma, Merkel Cell / therapy*
  • Cheek / surgery*
  • Combined Modality Therapy
  • Decision Making*
  • Facial Neoplasms / therapy*
  • Female
  • Humans
  • Prognosis
  • Quality of Life*
  • Radiotherapy, Adjuvant
  • Skin Neoplasms / therapy*
  • Surgical Flaps
  • Treatment Outcome