Visual recovery in treated bacterial keratitis

Ophthalmology. 2014 Jun;121(6):1310-1. doi: 10.1016/j.ophtha.2013.12.041. Epub 2014 Mar 5.

Abstract

Bacterial keratitis is a leading cause of visual impairment worldwide. However, the natural history of treated bacterial keratitis has not been well characterized. We performed a secondary analysis of the Steroids for Corneal Ulcers Trial (SCUT; clinicaltrials.gov #NCT00324168) to better characterize the rate of visual acuity improvement after successful antimicrobial treatment.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Aza Compounds / therapeutic use
  • Corneal Ulcer / drug therapy*
  • Corneal Ulcer / microbiology
  • Corneal Ulcer / physiopathology
  • Eye Infections, Bacterial / drug therapy*
  • Eye Infections, Bacterial / microbiology
  • Eye Infections, Bacterial / physiopathology
  • Female
  • Fluoroquinolones
  • Glucocorticoids / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Moxifloxacin
  • Prednisolone / analogs & derivatives*
  • Prednisolone / therapeutic use
  • Quinolines / therapeutic use
  • Recovery of Function / physiology*
  • Visual Acuity / physiology*

Substances

  • Anti-Bacterial Agents
  • Aza Compounds
  • Fluoroquinolones
  • Glucocorticoids
  • Quinolines
  • prednisolone phosphate
  • Prednisolone
  • Moxifloxacin

Associated data

  • ClinicalTrials.gov/NCT00324168