Small-molecule clinical trial candidates for the treatment of glioma

Drug Discov Today. 2014 Sep;19(9):1298-308. doi: 10.1016/j.drudis.2014.02.007. Epub 2014 Mar 4.

Authors

Saurabh Prabhu¹, Frederick Harris², Robert Lea¹, Timothy J Snape³

Affiliations

¹ School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
² School of Forensic and Investigative Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
³ School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK. Electronic address: tjsnape@uclan.ac.uk.

PMID: 24607526
DOI: 10.1016/j.drudis.2014.02.007

Abstract

The evaluation of new glioma treatments, currently in clinical trials, is undertaken.

Copyright © 2014 Elsevier Ltd. All rights reserved.

Publication types

Review

MeSH terms

Animals
Antineoplastic Agents / pharmacology*
Central Nervous System Neoplasms / drug therapy*
Central Nervous System Neoplasms / pathology
Clinical Trials as Topic
Drug Design
Glioma / drug therapy*
Glioma / pathology
Humans
Protein Kinase Inhibitors / pharmacology
Topoisomerase Inhibitors / pharmacology
Tubulin Modulators / pharmacology

Substances

Antineoplastic Agents
Protein Kinase Inhibitors
Topoisomerase Inhibitors
Tubulin Modulators