Population balance modeling: current status and future prospects

Annu Rev Chem Biomol Eng. 2014:5:123-46. doi: 10.1146/annurev-chembioeng-060713-040241. Epub 2014 Mar 3.

Abstract

Population balance modeling is undergoing phenomenal growth in its applications, and this growth is accompanied by multifarious reviews. This review aims to fortify the model's fundamental base, as well as point to a variety of new applications, including modeling of crystal morphology, cell growth and differentiation, gene regulatory processes, and transfer of drug resistance. This is accomplished by presenting the many faces of population balance equations that arise in the foregoing applications.

Keywords: biofilm growth; crystal morphology; gene regulatory processes; personalized medicine; stem cell differentiation; stochastic internal coordinates.

Publication types

  • Review

MeSH terms

  • Algorithms*
  • Cell Physiological Phenomena / physiology*
  • Crystallization / methods*
  • Gene Expression Regulation
  • Models, Theoretical*
  • Precision Medicine / methods
  • Stochastic Processes
  • Tissue Engineering / methods