Coulomb explosion imaged cryptochiral (R,R)-2,3-dideuterooxirane: unambiguous access to the absolute configuration of (+)-glyceraldehyde

Abstract

The absolute configuration of (R,R)-2,3-dideuterooxirane, which has been independently determined using Coulomb explosion imaging, has been unambiguously chemically correlated with the stereochemical key reference (+)-glyceraldehyde. This puts the absolute configuration of D(+)-glyceraldehyde on firm experimental grounds.

Keywords: Coulomb explosion imaging; absolute configuration; chirality; deuterium; glyceraldehyde.